Please suggest some solution. 

What I can suggest for achieving your requirement is using columnCssClass option of igGrid columns. This property is a space-separated list of CSS classes to be applied on the data cells of this column. You could set this property initially when creating columns collection as following:

<style>
      .colStyle {
         background-color:red;
      }
      .newColStyle {
         background-color:green;
      }
  </style>
.....
@(Html.Infragistics().Grid(Model)
  .ID("grid1")
  .Width("100%")
  .AutoCommit(true)
  .Height("500px")
  .AutoGenerateColumns(false)
  .PrimaryKey("Name")
        .Columns(col =>
      {
          col.For(c => c.ProductID).HeaderText("ProductID").Hidden(false).ColumnCssClass("colStyle");
          col.For(c => c.Name).HeaderText("Name");
          col.For(c => c.ReleaseDate).HeaderText("ReleaseDate");
          col.For(c => c.ProductNumber).HeaderText("Product Number");
          col.For(c => c.Col1).HeaderText("Col1");
          col.For(c => c.Col2).HeaderText("Col2");
      })
.Features(features =>
{
    features.Updating()
       .EditMode(GridEditMode.Row).ColumnSettings(cs => {
       cs.ColumnSetting().ColumnKey("Name").ReadOnly(true);        
   });
    //features.Filtering().Labels(x => { x.Yesterday("a").GreaterThan("ffff"); }).FilterDialogWidth("100");
    features.Selection().MultipleSelection(true);
    features.Sorting();
    features.Hiding();
    features.ColumnMoving();
    features.Paging().Type(OpType.Remote).PageSize(3);
})
.DataSourceUrl(Url.Action("GetData"))
.UpdateUrl(Url.Action("OrdersSaveData"))
.Render())

Please keep in mind that if this property is set it after initialization dataBind method should be called afterwards in order to re-render igGrid and apply the new css classes. For example if this is done on a button click the code will look like the following:

$("#changeCssBtn").click(function(){
       $("#grid1").igGrid("option", "columns")[0].columnCssClass = "newColStyle ";
       $("#grid1").igGrid("dataBind");
});

I hope you find this information helpful.

Please let me know if you have any further concerns or questions regarding this matter.

Thank you for using Infragistics components.